Compare and book 4 Star hotels in Otay Mesa, San Diego

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Check availability on Otay Mesa 4 Star Hotels

Top Otay Mesa 4 Star Hotels

Manchester Grand Hyatt San Diego
6 restaurants, breakfast, lunch, dinner served; seafood

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (2780)
"We had a great stay here. "
The price is 4.707.106 ₫
6.887.395 ₫ total
includes taxes & fees
28 Aug - 29 Aug
Manchester Grand Hyatt San Diego
Hyatt Regency Mission Bay Spa and Marina
Exterior

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
8.4 out of 10, Very good, (1508)
"Its a great hotel "
The price is 4.352.299 ₫
6.299.505 ₫ total
includes taxes & fees
28 Aug - 29 Aug
Hyatt Regency Mission Bay Spa and Marina
Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very good, (5837)
"Great location great price. "
The price is 3.998.806 ₫
5.285.668 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Wyndham San Diego Bayside
Embassy Suites by Hilton San Diego Bay Downtown
Lobby

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
9.0 out of 10, Wonderful, (1347)
"Great location and breakfast, would stay here again."
The price is 4.892.394 ₫
6.413.376 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Embassy Suites by Hilton San Diego Bay Downtown
Sheraton Mission Valley San Diego Hotel
Outdoor pool

Sheraton Mission Valley San Diego Hotel

4.0 star property
8.6 out of 10, Excellent, (1492)
"one of the best hotels!"
The price is 3.336.798 ₫
3.835.483 ₫ total
includes taxes & fees
25 Aug - 26 Aug
Sheraton Mission Valley San Diego Hotel
Paradise Point Resort & Spa
Property grounds

Paradise Point Resort & Spa

4.0 star property
8.6 out of 10, Excellent, (2213)
"Its amazing place for vacation "
The price is 4.122.857 ₫
6.069.565 ₫ total
includes taxes & fees
26 Aug - 27 Aug
Paradise Point Resort & Spa
Sheraton San Diego Resort
Room, 1 King Bed with Sofa bed, Marina View | View from room

Sheraton San Diego Resort

4.0 star property
8.2 out of 10, Very good, (2919)
"Excellent stay.. "
The price is 3.101.276 ₫
4.652.311 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Sheraton San Diego Resort
The Little Italy Hotel Downtown San Diego
View from room

The Little Italy Hotel Downtown San Diego

4.0 star property
8.0 out of 10, Very good, (1011)
"Great stay"
The price is 3.101.276 ₫
3.589.727 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Little Italy Hotel Downtown San Diego
Hilton San Diego Bayfront
Outdoor pool, pool loungers

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very good, (1663)
"Beautiful stay!"
The price is 4.693.965 ₫
6.708.204 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Hilton San Diego Bayfront
Marriott Marquis San Diego Marina
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)

Marriott Marquis San Diego Marina

4.0 star property
9.2 out of 10, Wonderful, (1813)
"Great place to stay."
The price is 5.729.476 ₫
7.816.923 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Marriott Marquis San Diego Marina
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2799)
"Great hotel "
The price is 4.711.837 ₫
6.670.808 ₫ total
includes taxes & fees
12 Sept - 13 Sept
Hard Rock Hotel San Diego
Hotel del Coronado, Curio Collection by Hilton
Lobby

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
8.0 out of 10, Very good, (1003)
"Very nice place for its age."
The price is 8.642.047 ₫
11.053.427 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Hotel del Coronado, Curio Collection by Hilton
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1010)
"Loved our stay very accommodating "
The price is 5.230.118 ₫
7.001.525 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Loews Coronado Bay Resort
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1624)
"Great place!"
The price is 2.483.649 ₫
2.874.725 ₫ total
includes taxes & fees
28 Aug - 29 Aug
Palihotel San Diego Gaslamp Quarter
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2854)
"Great stay"
The price is 4.031.133 ₫
4.633.779 ₫ total
includes taxes & fees
5 Sept - 6 Sept
Legacy Resort Hotel & Spa
Town and Country San Diego
2 outdoor pools, a heated pool, pool cabanas (surcharge), pool loungers

Town and Country San Diego

4.0 star property
8.6 out of 10, Excellent, (1250)
"this is really nice family hotel"
The price is 4.668.997 ₫
6.273.772 ₫ total
includes taxes & fees
16 Aug - 17 Aug
Town and Country San Diego
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Terrace/patio

The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Nice places to stay "
The price is 3.552.012 ₫
4.111.453 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
Hilton San Diego Mission Valley
Lobby

Hilton San Diego Mission Valley

4.0 star property
8.0 out of 10, Very good, (1897)
"We enjoyed our stay and very peaceful stay."
The price is 3.287.878 ₫
3.779.252 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Hilton San Diego Mission Valley
The Westin San Diego Bayview
Terrace/patio

The Westin San Diego Bayview

4.0 star property
8.6 out of 10, Excellent, (1003)
"Great stay and location for tourism "
The price is 3.775.409 ₫
5.139.312 ₫ total
includes taxes & fees
1 Sept - 2 Sept
The Westin San Diego Bayview
Lafayette Hotel & Club
Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (1070)
"everyone was lovely the ambience is everything, definitely coming back. "
The price is 6.412.808 ₫
7.358.697 ₫ total
includes taxes & fees
18 Aug - 19 Aug
Lafayette Hotel & Club
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa.
Pendry San Diego

Pendry San Diego

550 J Street, San Diego, CA
The price is 7.227.550 ₫ per night from 28 Aug to 29 Aug
7.227.550 ₫
9.699.963 ₫ total
28 Aug - 29 Aug
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa?
To book a 4-star hotel in Otay Mesa that fits your budget, take advantage of Expedia's handy filters. Browse the availability during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most economical stay first.

  • Search for the lowest price from 6.232.776 ₫

What's the difference between 5-star and 4-star hotels in Otay Mesa?
Treat yourself to refined living during your Otay Mesa escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually filled with amenities, including large beds, complimentary bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and memorable one. Concierge assistance, elegant décor and world-class dining are a few of the exclusive conveniences and services you'll likely be able to enjoy.
Does Otay Mesa have any 4-star all-inclusive resorts?
Finding your dream hotel in Otay Mesa is as easy as entering your travel dates and destination, and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your room, meals and activities, or choose a standard 4-star resort in or around this popular destination.