Medical Center District Travel Guide
San Antonio
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Stay near popular Medical Center District attractions
Top hotels in Medical Center District
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
The price is 2.323.097 ₫ per night from 13 Aug to 14 Aug
2.323.097 ₫
2.745.859 ₫ total
13 Aug - 14 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is 2.201.448 ₫ per night from 22 Aug to 23 Aug
2.201.448 ₫
2.602.308 ₫ total
22 Aug - 23 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,000 reviews)
"The friendly staff"
Reviewed on 10 Aug 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
The price is 2.354.228 ₫ per night from 16 Aug to 17 Aug
2.354.228 ₫
2.782.909 ₫ total
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
The price is 2.435.940 ₫ per night from 11 Sept to 12 Sept
2.435.940 ₫
2.894.659 ₫ total
11 Sept - 12 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (1,146 reviews)
"Parking was a little to crowded but over all good."
Reviewed on 10 Aug 2026
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
The price is 3.348.346 ₫ per night from 16 Aug to 17 Aug
3.348.346 ₫
3.958.046 ₫ total
16 Aug - 17 Aug
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
9.4/10 Exceptional! (5,057 reviews)
"I really enjoyed my stay."
Reviewed on 12 Aug 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
The price is 1.860.309 ₫ per night from 7 Sept to 8 Sept
1.860.309 ₫
2.718.348 ₫ total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, a fitness centre and parking (surcharge). Our guests praise the breakfast and the ...
8/10 Very good! (4,095 reviews)
"Breakfast was always too full. No seating area. It was also the same thing everyday. That was a plus when I booked to save on one meal a day but buy the second day we were over the sausage. The muffins could have hanged. We went to the pool on the last day and no security people were jumping in andrunni ..."
Reviewed on 12 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Medical Center District
Find the best Medical Center District areas for the activities you enjoy most.
Downtown San Antonio
A scenic riverfront great entertainment and top sights from Alamo to Alamodome – discover Downtown San Antonio, a destination also famous for its historic sites.
Photo by Sarah C.
Open Photo by Sarah C.
Uptown
If you're spending some time in Uptown, Alamo Quarry Market and San Antonio Zoo and Aquarium are top sights worth seeing.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.
