Medical Center District Travel Guide

San Antonio

Photo by Linda Cronan

Popular places to visit


Top hotels in Medical Center District

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is 2.340.146 ₫ per night from 31 Aug to 1 Sept
2.340.146 ₫
2.766.010 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (2,728 reviews)
"Hotel was in a nice area with lots of dining options nearby."

Reviewed on 25 Aug 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is 2.346.574 ₫ per night from 31 Aug to 1 Sept
2.346.574 ₫
2.788.626 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Antonio. Enjoy free parking, a free local area shuttle and room service. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,015 reviews)
"It was a comfortable and pleasant experience."

Reviewed on 25 Aug 2025

San Antonio Marriott Northwest Medical Center
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

2.5 out of 5
7203 Wurzbach Road, San Antonio, TX
The price is 2.424.476 ₫ per night from 7 Sept to 8 Sept
2.424.476 ₫
2.830.575 ₫ total
7 Sept - 8 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (996 reviews)
"Convenient to the medical center"

Reviewed on 25 Aug 2025

Fairfield Inn & Suites by Marriott San Antonio Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr, San Antonio, TX
The price is 2.582.594 ₫ per night from 4 Sept to 5 Sept
2.582.594 ₫
3.052.859 ₫ total
4 Sept - 5 Sept
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,005 reviews)
Sleep like a baby.
"I stay here cause they have the best, most comfortable beds ever!!"

Reviewed on 25 Aug 2025

Courtyard by Marriott Medical Center San Antonio
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
9700 West Military Drive, San Antonio, TX
The price is 2.553.606 ₫ per night from 10 Sept to 11 Sept
2.553.606 ₫
4.106.971 ₫ total
10 Sept - 11 Sept
includes taxes & fees
Stay at this 3.5-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, free parking and a lazy river. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (1,016 reviews)
"Love the lazy river & pool. Staff is friendly, property and rooms are very clean. Would stay again!"

Reviewed on 24 Aug 2025

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street, Dwyer/Main Plaza, San Antonio, TX
The price is 2.822.406 ₫ per night from 12 Sept to 13 Sept
2.822.406 ₫
3.336.553 ₫ total
12 Sept - 13 Sept
includes taxes & fees
Stay at this 4-star family-friendly hotel in San Antonio. Enjoy free Wi-Fi, room service and a 24-hour fitness centre. Our guests praise the restaurant and the ...
8/10 Very Good! (5,746 reviews)
"Everything is ok"

Reviewed on 26 Aug 2025

Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Medical Center District

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Northwest Los Angeles Heights

While Northwest Los Angeles Heights may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Alamo and Alamodome.

Northwest Los Angeles Heights
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Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Northwest Side
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Midtown

Unique features of Midtown include the river views and bars. Make a stop by The DoSeum or San Antonio Zoo and Aquarium while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

While visiting Tobin Hill, you might make a stop by sights like San Antonio River and Temple Beth-El.

Tobin Hill
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Uptown

If you're spending some time in Uptown, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Uptown

Medical Center District Travel Guide

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