Top hotels in Uptown
Hyatt Regency St. Louis at The Arch
315 Chestnut St, St. Louis, MO
The price is 3.128.748 ₫ per night from 22 Aug to 23 Aug
3.128.748 ₫
3.689.702 ₫ total
22 Aug - 23 Aug
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,979 reviews)
"Wonderful hotel steps away from the Gateway Arch! The staff were super helpful and the views were incredible even if you don’t have one of the many many rooms with a view of the arch. Good signage, parking options, and facilities."
Reviewed on 18 Aug 2025
Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street, St. Louis, MO
The price is 3.575.449 ₫ per night from 2 Sept to 3 Sept
3.575.449 ₫
4.180.737 ₫ total
2 Sept - 3 Sept
includes taxes & fees
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,957 reviews)
"so when you arrive you have 2 lanes you can use to go check in then go to garage after that"
Reviewed on 17 Aug 2025
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is 2.870.216 ₫ per night from 31 Aug to 1 Sept
2.870.216 ₫
3.343.457 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and ...
8.8/10 Excellent! (2,909 reviews)
"Very nice"
Reviewed on 16 Aug 2025
The Arch Convention Hotel
811 N 9th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is 2.813.731 ₫ per night from 31 Aug to 1 Sept
2.813.731 ₫
3.290.042 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a 24-hour fitness centre and parking (surcharge). Our guests praise the helpful ...
6.6/10 (1,019 reviews)
"Customer service was great. It was close to the things that we wanted to do."
Reviewed on 18 Aug 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is 2.706.016 ₫ per night from 31 Aug to 1 Sept
2.706.016 ₫
3.218.238 ₫ total
31 Aug - 1 Sept
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the bar and the helpful ...
8.6/10 Excellent! (1,004 reviews)
"Comfortable beds, clean & cool temperature for the hot weather."
Reviewed on 17 Aug 2025
Marriott St. Louis Grand
800 Washington Ave, St. Louis, MO
The price is 3.546.720 ₫ per night from 29 Aug to 30 Aug
3.546.720 ₫
4.218.080 ₫ total
29 Aug - 30 Aug
includes taxes & fees
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy breakfast (surcharge), 24-hour room service and a 24-hour fitness centre. Our guests praise the ...
8/10 Very Good! (1,010 reviews)
very good, but not an excellent experience
"The hotel was very clean and the staff were great! I particularly liked the water bottle filling machines on our floor and in the lobby. It was a bummer that only 2 elevators (of 5) worked when so many of us were coming back in from the ballgame on Saturday night, and that there are no restrooms ..."
Reviewed on 18 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Other neighbourhoods around Uptown
Historic Downtown Collinsville
Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
Mulberry Hills
Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Gateway Conference Center.
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
- Places of interest
- Hotels in Uptown by Star Rating
- Hotels in top Collinsville neighborhoods
- Search Uptown Hotel Brands
- Kruta Bakery
- St. Louis Union Station
- Gateway Arch
- Washington University in St. Louis
- St. Louis Zoo
- Dome at America’s Center
- City Museum
- America's Center Convention Complex
- Barnes Jewish Hospital
- Fox Theater
- St. Louis Aquarium at Union Station
- St. Louis Science Center
- River City Casino
- Chaifetz Arena
- St. Louis Art Museum
- The Edge
- Cahokia Mounds State Historic Site
- Cathedral Basilica of St. Louis