Search Boutique Hotels in Mission Valley

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mission Valley Boutique Hotels

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Mission Valley Boutique Hotels

Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1191)
"Amazing stay "
United States
Aaron
The price is 2.874.947 ₫
4.557.064 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel Republic San Diego, Autograph Collection
Presidential Suite, 2 Bedrooms | Living room | 36-inch LCD TV with digital channels, TV, pay films
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (867)
"Staff was amazing. Room was really nice and the view was PERFECT."
United States
Porscha
The price is 3.119.926 ₫
4.687.615 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Alma San Diego Downtown, a Tribute Portfolio Hotel
Property entrance
The Bristol Hotel San Diego

The Bristol Hotel San Diego

3.5 star property
Downtown San Diego
8.6 out of 10, Excellent, (1440)
"Great stay, clean room. Staff was very friendly as well. Would stay again. "
United States
Alexis
The price is 3.304.537 ₫
3.831.445 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Bristol Hotel San Diego
Exterior
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Hotel Indigo San Diego-Gaslamp Quarter by IHG

4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1003)
"great location, clean room, great staff"
United States
rahul
The price is 3.776.327 ₫
5.356.826 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Indigo San Diego-Gaslamp Quarter by IHG
Junior Suite, 1 King Bed, Ocean View | View from room
Pacific Terrace Hotel

Pacific Terrace Hotel

4.0 star property
Pacific Beach
9.6 out of 10, Exceptional, (1006)
"Had a great time! "
United States
Daniel
The price is 4.487.234 ₫
5.158.457 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Pacific Terrace Hotel
Exterior
Hercor Hotel - Urban Boutique

Hercor Hotel - Urban Boutique

3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1308)
"Great value and location "
United States
Andrew
The price is 2.218.053 ₫
2.444.183 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hercor Hotel - Urban Boutique
SANCTUARY SUITE | View from room
Tower23 Hotel

Tower23 Hotel

4.0 star property
Pacific Beach
9.6 out of 10, Exceptional, (1001)
"Great hotel!!"
Canada
RYAN
The price is 5.775.687 ₫
6.523.362 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Tower23 Hotel
Outdoor pool, pool loungers
Westgate Hotel

Westgate Hotel

4.5 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1002)
"Beautiful hotel, clean and very friendly staff! Beds were comfortable, we enjoyed our stay."
United States
Somer
Westgate Hotel
Front of property
The Pearl Hotel

The Pearl Hotel

4.0 star property
Point Loma
8.6 out of 10, Excellent, (1004)
"Everything was perfect, A much recommended place for people going on a trip to SD. I can’t forget the super comfy bed and pillows, The wife loved them !!"
United States
david
The price is 3.609.145 ₫
4.076.475 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Pearl Hotel
Outdoor pool, pool umbrellas
The Lodge at Torrey Pines

The Lodge at Torrey Pines

5.0 star property
Torrey Pines
9.2 out of 10, Wonderful, (878)
"Excellent all around!"
United States
Julie
The price is 10.105.367 ₫
13.462.184 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Lodge at Torrey Pines
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mission Valley Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's there to see and do in Mission Valley?
Visitors speak positively about this destination's breathtaking beach views, major shopping centres and zoo. Favorite activities and sights around Mission Valley include San Diego Zoo, Port of San Diego and Mission Bay. You might also want to see places such as Petco Park, Old Globe Theater and San Diego Museum of Art during your trip.
What's the best way to get to my boutique hotel in Mission Valley?
You have a few options for travelling to and around Mission Valley. The nearest major airport is San Diego, CA (MYF-Montgomery Field), which is located 2.8 mi (4.6 km) away, but San Diego, CA (SAN-San Diego Intl.) may also be an option. Walk to nearby metro stations such as Hazard Center Station, Mission Valley Center Station and Rio Vista Station.