Otay Mesa Travel Guide
San Diego
Popular places to visit
San Diego Zoo
Why not visit the animals who live at San Diego Zoo and see why this is a popular attraction in San Diego? Stroll along the area's seaside or experience its acclaimed art galleries.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's acclaimed art galleries and entertainment choices.
Mission Bay
Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.
SeaWorld
Make time to visit the sea life at SeaWorld, and find out why this is a popular attraction in San Diego. Discover the beautiful sunsets and top-notch restaurants in this walkable area.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Balboa Park
Balboa Park is just one of the places to see in San Diego, so why not enjoy the other things to explore during your travels? Stroll along the area's seaside or simply savour its top-notch restaurants.
Top hotels in Otay Mesa
Hotel del Coronado, Curio Collection by Hilton
Room was nice, walkability was great. On site amenities made the stay easy traveling with a toddler.
Reviewed on 18 Nov 2025
Hilton San Diego Mission Valley
I believe the parking price could be a bit more budget friendly for those staying at the hotel.
Reviewed on 25 Nov 2025
Legacy Resort Hotel & Spa
Everything was great
Reviewed on 22 Nov 2025
Hampton Inn & Suites by Hilton San Diego SeaWorld
I like the fact that the property was very clean The front desk were nice always asking if they needed something when I asked for sure she came back there and asked me if I had proceeded to syrup I said yes thank you I had an exciting excellent stay except that somebody stole from my hotel room a ...
Reviewed on 27 Nov 2025
Hard Rock Hotel San Diego
Loved this hotel!
Reviewed on 22 Nov 2025
Manchester Grand Hyatt San Diego
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Reviewed on 22 Nov 2025
Other neighbourhoods around Otay Mesa
East Village
Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Mid-City
While you're in Mid-City, take in top sights like Cal Coast Credit Union Open Air Theater or Viejas Arena, and hop on the metro to see more of the city at SDSU Transit Center Station or Alvarado Station.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Otay Mesa Travel Guide
- Places of interest
- Hotels in Otay Mesa by Star Rating
- Choose Your Otay Mesa Hotel Style
- Hotels in top San Diego neighborhoods
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- Cross Border Xpress
- San Diego Zoo
- San Diego Convention Center
- Mission Bay
- San Ysidro Border Crossing
- Port of San Diego
- Balboa Park
- Mission Beach
- Naval Base San Diego
- Las Americas Premium Outlets
- USS Midway Museum
- Seaport Village
- University of San Diego
- B Street Cruise Ship Terminal
- Sycuan Casino
- Naval Base Coronado
- Old Town San Diego State Park
- Snapdragon Stadium
- Waterfront Park
- Fashion Valley Mall
- Shelter Island
Choose Your Otay Mesa Hotel Style
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