Otay Mesa Travel Guide
San Diego
Popular places to visit
San Diego Zoo
Why not visit the animals who live at San Diego Zoo and see why this is a popular attraction in San Diego? Stroll along the area's beautiful beaches or experience its fascinating museums.
Mission Bay
Explore the great outdoors at Mission Bay, a popular spot to commune with nature in San Diego. Stroll along the beautiful beaches in this family-friendly area or visit its top-notch restaurants.
San Diego Convention Center
During your trip, find out what's happening in San Diego Convention Center, a top convention centre in San Diego. Experience the area's fascinating museums and acclaimed art galleries.
SeaWorld
Make time to visit the sea life at SeaWorld, and find out why this is a popular attraction in San Diego. Discover the beautiful sunsets and top-notch restaurants in this walkable area.
Petco Park
Catch an event at Petco Park during your trip to San Diego. Discover the top-notch restaurants and acclaimed art galleries in this walkable area.
USS Midway Museum
Study the exhibits at USS Midway Museum, a favourite museum in San Diego. Stroll along the area's seaside or simply savour its top-notch restaurants.
Top hotels in Otay Mesa
Hard Rock Hotel San Diego
The location can’t be. The hotels looking a bit worn. Most of the bars and restaurants weren’t open during a portion of my stay. The rooftop pool was OK, but the rest of the area looked very dated. My room was clean by the sink had significant water damage, and the wood was warped. It’s just looking ...
Reviewed on 2 May 2026
Paradise Point Resort & Spa
Great central location for visiting sites like Sea World and the San Diego Zoo with a short drive to fast food and highway access. We liked the multiple pools, beautiful garden/pond area and walking distance to the beach. The pool bathrooms could have been cleaner and there is a lot of bird poop ...
Reviewed on 2 May 2026
The Sofia Hotel
The Hotel Sofia is a great place to stay in downtown San Diego. Walking distance to anyplace you’d like to go. If not the trolley is just a block away. The staff is very friendly and answered any questions I had to my satisfaction. Will definitely be back.
Reviewed on 2 May 2026
The DEXTRO Little Italy, BW Premier Collection
Nice hotel. Clean and pleasent staff
Reviewed on 2 May 2026
Hotel del Coronado, Curio Collection by Hilton
It was very lovely.
Reviewed on 29 Apr 2026
Wyndham San Diego Bayside
Staff was very friendly considering it seemed they were short handed
Reviewed on 2 May 2026
Other neighbourhoods around Otay Mesa
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
North Park
North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.
Little Italy
Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Mission Valley
Known for its stunning beaches and popular shops, there's plenty to explore in Mission Valley. Check out top attractions like Mission Valley Mall and Fashion Valley Mall, and jump on the metro at Hazard Center Station or Mission Valley Center Station to see more of the city.
