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Check availability on Otay Mesa Casino Hotels

Our top choices for Otay Mesa hotels with a casino

3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1632)
"Nice rooms. Great food at all restaurants "
United States
Steve
Sycuan Casino Resort
Terrace/patio
Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
Imperial Beach
9.4 out of 10, Exceptional, (949)
"Great stay"
United States
Crystal
The price is 2.820.110 ₫
3.214.925 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Imperial Beach San Diego
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace
Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
National City
9.2 out of 10, Wonderful, (3525)
"Great friendly staff "
United States
mohammed
The price is 2.817.743 ₫
3.105.012 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Plus Marina Gateway Hotel
Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, pool loungers
Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego
2.0 star property
El Cajon
7.4 out of 10, Good, (1458)
"My stay here was pretty cool"
United States
Rana
The price is 1.826.758 ₫
2.013.275 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 El Cajon, CA - San Diego
Breakfast and dinner served
Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Courtyard by Marriott San Diego Mission Valley/Hotel Circle
3.5 star property
Mission Valley
8.4 out of 10, Very good, (1440)
"Good place to stay, and clean"
United States
Yuke
The price is 2.609.654 ₫
2.999.667 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott San Diego Mission Valley/Hotel Circle
View from room
The Rambler

The Rambler

The Rambler
3.0 star property
Chula Vista
9.2 out of 10, Wonderful, (1993)
"Nice staff, good location"
United Kingdom
Joshua
The price is 2.604.393 ₫
3.013.204 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Rambler
Terrace/patio
The Bower Coronado

The Bower Coronado

The Bower Coronado
5.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (150)
"Great place. Great rooftop bar. "
United States
Michael
The price is 5.421.873 ₫
7.279.411 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Bower Coronado
Desk, blackout curtains, iron/ironing board, free WiFi
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
San Ysidro
7.8 out of 10, Good, (1405)
"Excelente hotel "
Mexico
Adrian Andrés
The price is 1.841.490 ₫
2.098.194 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Outdoor pool, pool loungers
Carlton Oaks Lodge, an Ascend Collection Hotel

Carlton Oaks Lodge, an Ascend Collection Hotel

Carlton Oaks Lodge, an Ascend Collection Hotel
3.0 star property
Santee
8.2 out of 10, Very good, (1002)
"It was a great place to stay for a quick trip to the town."
United States
Marcia
The price is 2.580.717 ₫
3.417.543 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Carlton Oaks Lodge, an Ascend Collection Hotel
Standard Room, 1 King Bed, Non Smoking | Individually furnished, desk, free WiFi, bed sheets
Rodeway Inn El Cajon - San Diego East

Rodeway Inn El Cajon - San Diego East

Rodeway Inn El Cajon - San Diego East
2.0 star property
El Cajon
6.6 out of 10, (96)
"Lovely place! "
United States
L and M
The price is 1.565.267 ₫
1.721.794 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Rodeway Inn El Cajon - San Diego East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Otay Mesa Hotel Reviews

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Frequently asked questions

Searching for casino hotels in Otay Mesa?
Hoping to do some gaming in Otay Mesa? As luck would have it, you'll find Caliente Racetrack Casino, Jamul Casino, and Caliente Casino in the area, as well as much more to see and do. Visitors enjoy the family-friendly activities, beaches and shopping. You might be interested in the area's popular sights, which include San Diego Zoo, San Ysidro Border Crossing and Petco Park.
What is there to do in Otay Mesa?
You can head to Alameda Otay, Plaza Península Shopping Center or Plaza Rio Commercial Center to shop for the perfect souvenir. For a chance to experience some culture, you can visit North Island Credit Union Amphitheatre, Centro Cultural Tijuana or Fronton Jai Alai Palace. Additionally, you might want to add San Diego Zoo and San Ysidro Border Crossing to your itinerary.