Compare and book 3 Star hotels in Otay Mesa, San Diego
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Otay Mesa 3 Star Hotels
Top Otay Mesa 3 Star Hotels

Bay Club Hotel & Marina
Point Loma
9.2 out of 10, Wonderful, (3151)
The price is 3.014.320 ₫
3.464.810 ₫ total
includes taxes & fees
30 Nov - 1 Dec

Comfort Inn Sea World Area
Point Loma
8.6 out of 10, Excellent, (3063)
The price is 2.241.535 ₫
2.576.532 ₫ total
includes taxes & fees
9 Dec - 10 Dec

Comfort Inn San Diego Airport At The Harbor
Point Loma
7.8 out of 10, Good, (1156)
The price is 1.757.363 ₫
1.984.854 ₫ total
includes taxes & fees
8 Dec - 9 Dec

Best Western Plus Marina Gateway Hotel
National City
9.2 out of 10, Wonderful, (3461)
The price is 3.138.268 ₫
3.458.160 ₫ total
includes taxes & fees
30 Nov - 1 Dec

Hampton Inn & Suites by Hilton San Diego SeaWorld
Point Loma
9.2 out of 10, Wonderful, (353)
The price is 3.143.423 ₫
3.613.091 ₫ total
includes taxes & fees
18 Dec - 19 Dec

Days Inn by Wyndham San Diego Hotel Circle
Mission Valley
8.0 out of 10, Very good, (2413)
The price is 2.331.196 ₫
2.679.593 ₫ total
includes taxes & fees
9 Dec - 10 Dec

Best Western Seven Seas
Mission Valley
7.8 out of 10, Good, (3031)
The price is 2.229.668 ₫
2.562.893 ₫ total
includes taxes & fees
9 Dec - 10 Dec

The Dana on Mission Bay
Mission Bay
8.8 out of 10, Excellent, (3891)
The price is 4.192.989 ₫
5.346.984 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Otay Mesa.

Hotel del Coronado, Curio Collection by Hilton
1500 Orange Ave Coronado CA
The price is 10.064.874 ₫ per night from 15 Dec to 16 Dec
10.064.874 ₫
12.637.766 ₫ total
15 Dec - 16 Dec
includes taxes & fees
8.4/10 Very Good! (1,013 reviews)
Still don't see what you're looking for?
See all properties in Otay Mesa.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Otay Mesa Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld
10/10 Excellent

The DEXTRO Little Italy, BW Premier Collection
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
Hotels in Otay Mesa by Star Rating
Areas of Otay Mesa
Accommodation near Otay Mesa attractions
- Hotels near Cross Border Xpress
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Hotel Circle
- Hotels near Petco Park
- Hotels near Mission Beach
- Hotels near Marine Corps Recruit Depot
- Hotels near Naval Base San Diego
- Hotels near Coronado Beach
- Hotels near Las Americas Premium Outlets
- Hotels near Seaport Village
- Hotels near San Diego State University
- Hotels near B Street Cruise Ship Terminal
- Hotels near Naval Base Coronado
Choose Your Otay Mesa Hotel Style
- Beach Resorts & Hotels in Otay Mesa
- Business Hotels in Otay Mesa
- Casino Hotels in Otay Mesa
- Cheap Hotels in Otay Mesa
- Family-Friendly Hotels in Otay Mesa
- Golf Hotels in Otay Mesa
- Historic Hotels in Otay Mesa
- Hotels Suites in Otay Mesa
- Hotels near Museums in Otay Mesa
- Hotels with Air Conditioning in Otay Mesa
- Hotels with Breakfast in Otay Mesa
- Hotels with Connecting Rooms in Otay Mesa
- Hotels with Entertainment in Otay Mesa
- Hotels with Gym in Otay Mesa
- Hotels with Laundry Service in Otay Mesa
- Hotels with Parking in Otay Mesa
- Hotels with Wifi in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Shopping Hotels in Otay Mesa
- Spa Hotels in Otay Mesa










































































