Compare and book 5 Star hotels in Otay Mesa, San Diego

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Check availability on Otay Mesa 5 Star Hotels

Tonight
27 Jun - 28 Jun
Tomorrow
28 Jun - 29 Jun
This weekend
27 Jun - 29 Jun
Next weekend
4 Jul - 6 Jul

Top Otay Mesa 5 Star Hotels

Pendry San Diego
3 restaurants, breakfast, lunch, dinner served; seafood

Pendry San Diego

5.0 star property
9.2 out of 10, Wonderful, (1000)
"Perfect from checking in to staying & checking out! "
The price is 6.915.175 ₫
9.342.382 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Pendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego
Lobby

The US Grant, a Luxury Collection Hotel, San Diego

5.0 star property
9.0 out of 10, Wonderful, (1002)
"staff was awesome specially Mark and Brooks with concierge"
The price is 6.853.852 ₫
7.946.699 ₫ total
includes taxes & fees
28 Jul - 29 Jul
The US Grant, a Luxury Collection Hotel, San Diego
Beach Village at The Del, LXR Hotels & Resorts
Exterior

Beach Village at The Del, LXR Hotels & Resorts

5.0 star property
9.2 out of 10, Wonderful, (102)
"The Del is amazing! The staff are top notch and the amenities are endless! We cannot wait to go back!"
The price is 27.725.938 ₫
31.857.348 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Beach Village at The Del, LXR Hotels & Resorts
The Bower Coronado
Interior

The Bower Coronado

5.0 star property
9.6 out of 10, Exceptional, (19)
"Great property in a great part of town. "
The price is 8.901.004 ₫
11.095.854 ₫ total
includes taxes & fees
8 Jul - 9 Jul
The Bower Coronado
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Otay Mesa.
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

1 Market Pl, San Diego, CA
The price is 4.936.680 ₫ per night from 2 Jul to 3 Jul
4.936.680 ₫
7.152.178 ₫ total
2 Jul - 3 Jul
includes taxes & fees
9/10 Wonderful! (2,778 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Otay Mesa?
How much you pay for a 5-star hotel in Otay Mesa can vary according to when you want to travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to score the best deal on a luxurious stay.

  • Search for the lowest price per night from 4.936.680 ₫

What makes a hotel 5 stars in Otay Mesa?
From gourmet dining venues and 24-hour fitness centres to swimming pools and deluxe bedding, the 5-star experience in Otay Mesa is all about luxury and comfort. But it calls for more than just upscale perks to receive a 5-star rating. Stays also have to offer remarkable guest services like in-room beauty treatments, on-site laundry and concierge services.
Are there any 5-star all-inclusive resorts in Otay Mesa?
Use our filters to find a luxury getaway in Otay Mesa where most of what you need is included in the price. Next, refine your results for resorts that have a rating of 5 stars and are described as "All inclusive." The main thing on the schedule at these stays? Relaxation and indulgence.