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Check availability on Otay Mesa Business Hotels

Tonight
27 Nov - 28 Nov
Tomorrow
28 Nov - 29 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Top Otay Mesa Business Hotels

Exterior
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
Otay Mesa
8.0 out of 10, Very good, (1548)
"Good comfortable beds good breakfast "
United States
Andrey
The price is 3.401.988 ₫
3.869.762 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa

2.5 star property
Otay Mesa
7.2 out of 10, Good, (1004)
"Beautiful place "
United States
Joe
The price is 2.610.729 ₫
2.969.705 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Quality Suites San Diego Otay Mesa
Outdoor pool
Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG

3.5 star property
Mission Valley
7.8 out of 10, Good, (1029)
"Good value Nice place to stay "
United States
John
The price is 2.194.150 ₫
2.533.346 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Crowne Plaza San Diego - Mission Valley by IHG
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (677)
"Great staff, great location, great value. "
United States
Juan
The price is 2.405.126 ₫
2.788.624 ₫ total
includes taxes & fees
24 Dec - 25 Dec
The DEXTRO Little Italy, BW Premier Collection
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1825)
"Great location , beautiful restaurant and nice grounds"
United States
Dawn
The price is 2.136.051 ₫
3.771.514 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton San Diego Bayfront
3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sycuan Casino Resort

Sycuan Casino Resort

4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1630)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
Sycuan Casino Resort
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1036)
"Spacious rooms , great staff "
United States
Jessica
The price is 3.119.689 ₫
4.381.618 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Westin San Diego Bayview
Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

4.0 star property
University Heights
9.4 out of 10, Exceptional, (1293)
"Loved everything, I could stay there forever"
United States
Mariana
The price is 5.959.846 ₫
6.838.923 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Lafayette Hotel & Club
Outdoor wedding area
Four Points by Sheraton San Diego

Four Points by Sheraton San Diego

3.5 star property
Kearny Mesa
8.0 out of 10, Very good, (1010)
"Overall, I had a great stay. "
United States
Joseph Payne Williams,
The price is 2.030.567 ₫
2.334.035 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Four Points by Sheraton San Diego
Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1170)
"Amazing stay "
United States
Aaron
The price is 3.035.444 ₫
4.283.969 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Republic San Diego, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Otay Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"Elijah was awesome!!! He addressed all of my concerns and went above and beyond to make sure all of our needs were meant. Very nice and super friendly (: "
Ismael 1-night trip
Posted 2 days ago
The DEXTRO Little Italy, BW Premier Collection

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Frequently asked questions

Why book your business-friendly hotel in Otay Mesa with Expedia?
Here at Expedia, our business is to help you land an excellent stay at the right price. From upmarket, corporate-friendly retreats to affordable hotels loaded with amenities, you'll have your next work trip organised in a few quick clicks.
How can I find cheap business-friendly hotels in Otay Mesa?
Select the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business-friendly hotels in Otay Mesa. Then refine your search by your nightly budget. Looking for properties outside the city centre is another good way to save.