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Top Otay Mesa Spa Hotels

Sycuan Casino Resort

4.0 star property
El Cajon
  • A full-service spa
  • Massages
  • Steam room
  • Sauna
9.2 out of 10, Wonderful, (1632)
Spa Ritual beckons with couples treatment rooms, deep-tissue massages, and rejuvenating body wraps. Guests luxuriate in the sauna and steam room between dips in 3 outdoor pools with a lazy river. After pampering facials, 7 restaurants offer delicious dining options.
Sycuan Casino Resort

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
  • A full-service spa
  • Massages
  • Steam room
  • Sauna
8.6 out of 10, Excellent, (1829)
Soothing bay views complement this full-service spa sanctuary offering aromatherapy, body wraps, and rejuvenating facials. Relax in the steam room, sauna, or hot tub after treatments, then enjoy poolside relaxation or fitness classes at the health club.
The price is 2.145.890 ₫
3.782.953 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton San Diego Bayfront

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
  • Massages
  • Outdoor pool
  • Near the beach
8.6 out of 10, Excellent, (1039)
Rejuvenate tired muscles with expert spa treatments in dedicated massage rooms at this bayfront retreat. Guests alternative between hot tub soaks and garden strolls, complemented by fitness facilities and poolside relaxation. Attentive staff ensures a serene wellness experience.
The price is 3.119.808 ₫
4.381.785 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Westin San Diego Bayview

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
  • A full-service spa
  • Massages
  • 3 outdoor pools
  • Sauna
  • Near the beach
8.4 out of 10, Very good, (1573)
Soothing body wraps and expert massages await in this hotel's full-service spa retreat. Guests rave about skilled practitioners and tranquil ambiance while enjoying three outdoor pools, waterslides, and stunning marina views between treatments.
The price is 4.011.181 ₫
6.005.995 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hyatt Regency Mission Bay Spa and Marina

Handlery Hotel

3.5 star property
Mission Valley
  • Massages
  • Outdoor pool
8.2 out of 10, Very good, (2219)
Massage therapy and facials await at this hotel's treatment rooms, offering a serene wellness escape. Surrounded by gardens and complemented by a heated outdoor pool, hot tub, and fitness centre, guests experience complete rejuvenation with attentive staff nearby.
The price is 2.565.996 ₫
2.949.484 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Handlery Hotel

Loews Coronado Bay Resort

4.0 star property
Silver Strand
  • A full-service spa
  • Massages
  • Steam room
  • Sauna
  • On the beach
8.8 out of 10, Excellent, (1068)
Surrounded by stunning views, this waterfront sanctuary pampers guests with aromatherapy, hot stone massages, and reflexology treatments in couples or outdoor spaces. Unwind in the sauna, steam room, or one of 3 pools before exploring gardens and enjoying sunset firepit moments.
The price is 4.720.588 ₫
6.520.213 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Loews Coronado Bay Resort

Best Western Plus Marina Gateway Hotel

3.5 star property
National City
  • Outdoor pool
9.2 out of 10, Wonderful, (3462)
Rejuvenating spa treatments await at this bayfront wellness retreat with a serene hot tub and 24-hour fitness centre. Guests praise the exceptionally clean rooms, tropical landscaping, and attentive staff who create a truly restorative experience.
The price is 3.138.506 ₫
3.458.423 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Marina Gateway Hotel

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
  • A full-service spa
  • Massages
  • Outdoor pool
  • Sauna
9.2 out of 10, Wonderful, (2967)
Surrounded by tranquil ambiance, Legacy Resort's spa sanctuary offers deep-tissue, hot stone, and Swedish massages alongside rejuvenating facials. Guests appreciate the pristine facilities, attentive staff, and peaceful atmosphere while enjoying luxurious treatments in a serene setting.
The price is 3.304.412 ₫
3.798.257 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Legacy Resort Hotel & Spa

San Diego Mission Bay Resort

4.0 star property
Mission Bay
  • A full-service spa
  • Massages
  • Outdoor pool
  • On the beach
8.4 out of 10, Very good, (1309)
Spa Brezza invites weary travellers into a sanctuary of wellness with rejuvenating massage treatments amid Mediterranean-inspired surroundings. White sand beaches, serene gardens, and poolside cabanas complement the spa experience, while two restaurants serve delectable American cuisine after a day of pampering.
The price is 4.412.036 ₫
6.260.450 ₫ total
includes taxes & fees
9 Dec - 10 Dec
San Diego Mission Bay Resort

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
  • Massages
  • Outdoor pool
9.2 out of 10, Wonderful, (2068)
Luxurious massage therapies soothe tired muscles while the outdoor hot tub beckons beneath open skies. Sports enthusiasts appreciate the prime location near Petco Park, while families enjoy nearby attractions after indulging in the hotel's spectacular wellness offerings.
The price is 4.684.986 ₫
6.624.647 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Omni San Diego Hotel at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa Hotel Reviews

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Frequently asked questions

Looking for a spa hotel in Otay Mesa?
Treat yourself to some pampering and book a hotel with a spa. Enjoy the theatre scene and shops in Otay Mesa—your day trip starts here. Discover the beaches and many popular restaurants during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Otay Mesa?
Enjoy Otay Mesa with a stop at San Diego Zoo, San Ysidro Border Crossing and Petco Park. If you have spare time during your trip, you might want to make a stop at Rosarito Beach and Port of San Diego.
What is a Otay Mesa spa hotel?
Spa hotels in Otay Mesa provide lodging and have a full on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.